Treatment of severe nail psoriasis with etanercept.
نویسندگان
چکیده
resistant rickets type IIA, a compound heterozygote for mutations in the Vitamin D receptor gene (VDR) in which the phenotype of atrichia with papular lesions was identical to that seen in patients carrying mutations in the HR gene. It is hypothesized that the VDR and HR genes, which are both zinc-finger proteins, may be in the same genetic pathway that controls postnatal cycling of the hair follicle.[4]
منابع مشابه
Nail Lichen Planus: Successful Treatment with Etanercept
BACKGROUND: Etanercept is a fully human tumor necrosis factor a receptor fusion protein that binds tumor necrosis factor a with greater affinity than natural receptors. Biologics are widely used in the treatment of psoriasis and psoriasis arthritis and may represent a new therapeutic option for some patients with psoriatic nail disease. CASE REPORT: We report a case of lichen planus limited to ...
متن کاملTreatment of nail psoriasis: best practice recommendations from the Medical Board of the National Psoriasis Foundation.
IMPORTANCE Nail psoriasis can be difficult to treat and has a significant effect on quality of life. Relatively few controlled trials evaluating treatments for nail psoriasis have been published. There is an unmet need for treatment recommendations to guide therapeutic decisions. OBJECTIVE To develop treatment recommendations for nail psoriasis from the Medical Board of the National Psoriasis...
متن کاملSafety and efficacy of apremilast through 104 weeks in patients with moderate to severe psoriasis who continued on apremilast or switched from etanercept treatment: findings from the LIBERATE study
BACKGROUND Apremilast, an oral phosphodiesterase-4 inhibitor, has demonstrated efficacy in patients with moderate to severe psoriasis. OBJECTIVE To evaluate long-term efficacy and safety of apremilast in biologic-naive patients with moderate to severe plaque psoriasis and safety of switching from etanercept to apremilast in the phase 3b LIBERATE trial. METHODS Two hundred fifty patients wer...
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Background: Nail psoriasis affects approximately 50% of psoriasis patients and in many cases causes functional impairment in manual dexterity, pain and psychological stress. It is often overlooked, not treated effectively. Physicians often believe that the condition is difficult to treat. The risks of systemic conventional therapy are not justified and the difficulty of delivering effective top...
متن کاملEtanercept in psoriasis: the evidence of its therapeutic impact
INTRODUCTION Psoriasis is a chronic inflammatory skin condition for which there is no cure. Treatment options are designed to control the disease symptoms and improve patients' quality of life, and physical and mental function. Established treatments can be effective but are also limited by tolerability, convenience, cosmetic, and economic issues. Etanercept, a fully human soluble tumor necrosi...
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ورودعنوان ژورنال:
- Indian journal of dermatology, venereology and leprology
دوره 77 1 شماره
صفحات -
تاریخ انتشار 2011